List of Publications

 

Professor Tan, Nget Hong

Department of Molecular Medicine

Faculty of Medicine, University of Malaya

Kuala Lumpur, Malaysia

 

 

  1. Tan, N.H. and Kaiser, E.T. (1976): Studies on the solid phase synthesis of basic pancreatic trypsin inhibitor (Kunitz) and the characterization of the synthetic material. Journal of Organic Chemistry, 41, 2787-2793.
  2. Tan, N.H. and Kaiser, E.T. (1977): Synthesis and characterization of a pancreatic trypsin inhibitor homologue and a model inhibitor. Biochemistry, 16, 1531-1541.
  3. Chan, R.L., Tan, N.H. and Kaiser, E.T. (1978): Synthesis and characterization of a metal-binding peptide fragment of human carbonic anhydrase B. Bioorganic Chemistry, 7, 313-332.
  4. Tan, N.H., Ho, M.Y., Ramasamy, P. and Chin, K.O. (1979): Isolation and characterization of trypsin inhibitors from the seed of four-angled bean (Psophocarpus tetragonolobus). In: Food and Nutritional Biochemistry (Khor, H.T., Ong, K.K. and Oo, K.C. eds), Proceedings of the Second Symposium of Federation of Asian and Ocean Biochemists, pp86-102. Malaysian Biochemical Society.
  5. Khor, H.T., Tan, N.H. and Wong, K.C. (1980): Winged bean seed, a potential food source for the tropics. Proc. Mal. Biochem. Soc., 6, 157-162.
  6. Iskandar, M., Lowe, E.S.H. and Tan, N.H. (1980): The extractability of winged bean seed proteins and some properties of the extractable trypsin inhibitors. Proc. Mal. Biochem. Soc., 6, 148-156.
  7. Tan, N.H. and Ho, M.Y. (1980): Isolation and preliminary characterization of the major lethal toxin of Malayan cobra venom. Malaysian Journal of Sciences, 6A, 111-116.
  8. Tan, N.H. and Mok, S.L. (1980): Chromatographic fractionation and some properties of the toxic fractions of Naja naja sputatrix (Malayan cobra) venom. Proc. Mal. Biochem. Soc., 6, 19-28.
  9. Tan, N.H. (1981): The preparation of potent Malayan cobra antivenin. Proc. Mal. Biochem. Soc., 7, 24-28.
  10. Tan, N.H. (1982): Cardiotoxins from the venom of Malayan cobra. Archives of Biochemistry and Biophysics, 218, 51-58.
  11. Tan, N.H. (1982): Acidic phospholipase A2 from the venom of common sea snake (Enhydrina schistosa). Biochimica et Biophysica Acta, 717, 503-508.
  12. Tan, N.H. (1982): Isolation and preliminary characterization of two toxic phospholipase A2 from the venom of Malayan cobra. Biocheimica et Biophysica Acta 719, 599-605.
  13. Tan, N.H. (1982): Chromatographic fractionation of the Malayan pit viper venom. Proc. Mal. Biochem. Soc., 8, 65-68.
  14. Tan, N.H. (1982) Toxic phospholipase A2 from the venom of Malayan cobra. Paper presented at the 12th International Congress of Biochemistry, Australia, 15-21st Aug, 1982.
  15. Tan, N.H., Lowe, E.S.H. and Iskandar, M. (1982): The extractability of winged bean trypsin inhibitors. Journal of Science of Food and Agriculture, 33, 1327-1330.
  16. Tan, N.H. and Wong, K.C. (1982): Thermal stability of trypsin inhibitor activity in winged bean. Journal of Agricultural and Food Chemistry, 30, 1140-1143.
  17. Tan, N.H., Zubaidah, A.R. and Wong, K.C. (1982): Protease inhibitors in winged beans. Proc. Mal. Biochem. Soc., 8, 151-154.
  18. Tan, N.H., Zubaidah, A.R. and Wong, K.C. (1982): Naturally occurring toxicants of winged beans. Proc. Polymer Seminar and IKM Chemical Conference, 1982, pp189-192.
  19. Khor, H.T., Tan, N.H. and Wong, K.C. (1982): Chemistry of winged bean seeds. Proceedings of the Polymer Seminar and IKM Chemical Conference, 1982, pp 193-200.
  20. Oo, K.C. and Tan, N.H. (1982): Purification of lipase from developing oil palm seedling. Proc. Mal. Biochem. Soc., 8, 53-59.
  21. Khor, H.T., Tan, N.H. and Wong, K.C. (1982): The protein, trypsin inhibitor and lipid of the winged bean (Psophocarpus tetragonolobus) seeds. Journal of Science of Food and Agriculture, 33, 996-1000.
  22. Khor, H.T., Tan, N.H. and Wong, K.C. (1983): The chemistry and the potential of winged bean seed lipids as a new source of vegetable oil. In ‘Fats For the Future” (Brooker, S.G., Renwick, A., Hannan, S.F. and Eyres, L. Eds), p59-63.
  23. Tan, N.H. (1983): Gel filtration fractionation of winged bean proteins. Journal of the Science of Food and Agriculture, 34, 203-208.
  24. Tan, N.H., Zubaidah, A.R., Khor, H.T. and Wong, K.C. (1983): Winged bean tannin levels, phytate contents and hemagglutinating activity. Journal of Agric. And Food Chem., 31, 916-917.
  25. Tan, N.H., Zubaidah, A.R., Khor, H.T. and Wong, K.C. (1983): Growth inhibition of rats fed winged bean meal. In: “Biochemistry in Agriculture” (Marziah, M. Ed.). pp82-85.
  26. Tan, N.H. (1983): The problem of winged bean protein digestibility. In: “Biochemistry in Agriculture” (Marziah, M.Ed.) p16-19.
  27. Tan, N.H. (1983): Venoms and antivenoms. Paper presented at the Malaysian Society of Pathologists Seminar on Snake-bites in Malaysia. Petaling Jaya, Malaysia, Feb 18th, 1983.
  28. Tan, N.H. (1983): Improvement of Malayan cobra antivenom. Toxicon, 21, 75-79.
  29. Tan, N.H. (1983): Isolation and characterization of two toxins from the venom of the Malayan cobra (Naja naja sputatrix). Toxicon, 21, 201-207.
  30. Tan, N.H., Zubaidah, A.R. and Wong, K.C. (1984): The nutritional quality of winged bean seed protein. Proc. Mal. Biochem. Soc., 10, 127-132.
  31. Tan, N.H., Zubaidah, A.R., Khor, H.T. and Wong, K.C. (1984): Chymotrypsin inhibitor activity in winged bean. Journal of Agric. And Food Chemistry, 32, 163-166.
  32. Tan, N.H., Wong, K.C. and de Lumen B.O. (1984): Relationships of tannin levels and trypsin inhibitor activity with the in vitro protein digestibilities of winged beans. Journal of Agric. And Food Chemistry 32, 819-823.
  33. Tan, N.H. (1984): Comments on the efficacy of IMR’s Malayan pit viper antivenom.  In: Reports on Malayan pit viper Antivenom.  Institute for Medical Research, Kuala Lumpur, Malaysia, p.35.
  34. Tan, N.H. and Ong, S.C. (1984): Isolation of an arginine ester hydrolase from the venom of ular kapak pantai laut (Trimeresurus purpureomaculatus). Proc. Mal. Biochem. Soc., 10, 79-81.
  35. Tan, N.H. (1984): Isolation of the major arginine amidase from the venom of the Malayan pit viper (Agkistrodon rhodostoma). Proceedings of the Sixth European Symposium on Animal, Plant and Microbial Toxins. Basle, Switzerland, 1984, p126.
  36. Tan, N.H. and Kanthimathi, M.S. (1985): Variation in the composition of Agkistrodon rhodostoma venom from different geographical origins. Toxicon, 23, 614.
  37. Tan, N.H. (1985): Arginine ester hydrolases from the venom of Trimeresurus purpureomaculatus. Toxicon, 23, 614.
  38. Tan, N.H., Tan, C.S. and Kanthimathi, M.S. (1985): Ion-exchange chromatographic fractionation of Malayan pit viper venom. Proc. Mal. Biochem. Soc., 11, 149-151.
  39. Tan, N.H. and Kanthimathi, M.S. (1985): Arginine ester hydrolases from Malayan pit viper venoms. Proc. Mal. Biochem. Soc., 11, 271-275.
  40. Chua, C.L., Tan, N.H. and Khor, H.T. (1985): Studies on the lipolytic activity of lipases on palm oil and other fats. Proc. Mal. Biochem. Soc., 11, 79-82.
  41. Chua, C.L., Tan, N.H. and Khor, H.T. (1986): Enzyme catalyzed hydrolysis of palm oil. J. Am. Oil Chem. Soc., 63, 538-540.
  42. Chua, C.L., Tan, N.H. and Khor, H.T. (1986): The production of fatty acids and glycerol by enzymatic methods. Paper presented at the 12th Malaysian Biochemical Society Annual Conference, Bangi, Malaysia.
  43. Khor, H.T., Chua, C.L. and Tan, N.H. (1986): Palm oil splitting with a lipase from candida rugosa. In: Contemporary Themes in Biochemistry, (Kon, O.L., Chung, M.C.M., Hwang, P.L.H., Leong, S.F., Loke, K.H., Thiyagarajah, P. and Wong, P.T.H. Eds), ICSU Press: Singapore, pp 486-487.
  44. Tan, N.H. and Roslina, M.N. (1986): Fractionation of winged bean (Psophocarpus tetragonolobus) seed proteins. Proc. Mal. Biochem. Soc., 12, 48-51.
  45. Tan, N.H. (1986): Evaluation of the nutritive value of winged bean (Psophocarpus tetragonolobus) seed protein. In: Contemporary Themes in Biochemistry, (Kon, O.L., Chung, M.C.M., Hwang, P.L.H., Leong, S.F., Loke, K.H., Thiyagarajah, P. and Wong, P.T.H. Eds), ICSU Press: Singapore, pp 222-223.
  46. Tan, N.H. (1986): Biochemical studies on Malayan pit viper venom. Paper presented at the 22nd Annual Scientific Seminar of the Malaysian Society of Parasitology and Tropical Medicine, Feb 28th-Mar 1st, 1986, Kuala Lumpur, Malaysia.
  47. Tan, N.H., Kanthimathi, M.S. and Tan, C.S. (1986): Enzymatic activities of Calloselasma rhodostoma venom. Toxicon, 24, 626-630
  48. Tan, N.H., Ong, S.C. and Arunmozhiarasi, A. (1987): Acidic phospholipase A from the venom of Malayan cobra. Proc. Mal. Biochem. Soc. 13, 160-167.
  49. Tan, N.H. and Tan, C.S. (1987): Biochemical studies of Mangrove pit viper venom. Proc. Mal. Biochem. Soc., 13, 148-153.
  50. Tan, N.H. and Tan, C.S. (1987): Comparative studies of snake venom enzymes. Proc. Mal. Biochem. Soc., 13, 154-159.
  51. Tan, N.H. and Tan, C.S. (1987): A simple and rapid assay of phospholipase A using acidometric method. Proc. Mal. Biochem. Soc. 13, 24-29.
  52. Tan, N.H. and Tan, C.S. (1987): Studies on the stability of snake venom phospholipase A, protease, arginine ester hydrolase and coagulant enzyme at 37C. Proc. Mal. Biochem. Soc., 13, 168-173.
  53. Tan, N.H., Ong, S.C. and Tan, C.S. (1987): Evaluation of the acidimetric assay of phospholipase A using lipoprotein substrate. Paper presented at the International Meeting on Biochemistry, Aug 17th-22nd, 1987, Beijing, China.
  54. Tan, N.H., Chua, C.L. and Khor, H.T. (1987): Adsorption of Candida rugosa lipase on florisil and the properties of the immobilized lipase. Paper presented at the International Meeting on Biochemistry, Aug 17th-22nd, Beijing, China.
  55. Tan, N.H. and Tan, C.S. (1987): Enzymatic activities of Malayan cobra venom. Toxicon, 25, 1249-1253.
  56. Khor, H.T., Tan, N.H. and Chua, C.L. (1987): Palm oil splitting by an immobilized lipase. J. Amer. Oil Chem. Soc., 64, 1296 (Abstract)
  57. Zainuddin, J., Olivo, M., Paramsothy, M., Tan, N.H. and Low, K.S. (1987): Nuclear imaging of 99mTc labelled haematoporphyrin derivative in tumor bearing rats. Paper presented at the Asian Physics Symposium, Oct 15th-17th, 1987, Kuala Lumpur, Malaysia.
  58. Tan, N.H. and Tan, C.S. (1988): Thermal stability of snake venom enzymatic activities. Toxicon, 26, 42.
  59. Tan, N.H. and Tan, C.S. (1988): Acidimetric assay for phospholipase A using egg yolk suspension substrate. Analytical Biochemistry 170, 282-288.
  60. Tan, N.H. and Tan, C.S. (1988): Partial purification of acetylcholinesterase from the venom of shore pit viper (Trimeresurus purpureomaculatus). Toxicon, 26, 505-508.
  61. Tan, N.H., Arunmozhiarasi, A. and Tan, C.S. (1988): Comparative enzymology of Asian cobra venoms. Toxicon, 26, 42-43.
  62. Geh, S.L. and Tan, N.H. (1988): Biochemical and pharmacological characteristics of an acidic phospholipase A from the venom of Malayan cobra. Toxicon, 26,22.
  63. Tan, N.H. and Tan, C.S. (1988): A comparative study of cobra (Naja) venom enzymes. Comparative Biochemistry and Physiology, 90B, 745-750.
  64. Tan, N.H. and Tan, C.S. (1988): Biological properties of Trimeresurus purpureomaculatus venom and its fractions. Toxicon 26, 989-996.
  65. Tan, N.H. (1988): The effect of essential amino acid profile on the protein efficiency ratio of winged bean (Psophocarpus tetragonolobus) seed protein. Asia Pacific Communications in Biochemistry, 2, 77-80.
  66. Saifuddin, M.N. and Tan, N.H. (1988): Purification of a hemorrhagin from king cobra venom. In: Advances in Biochemistry and Biotechnology in Asia and Oceania (Sipat, A., Ampon, K., Perumal, P., Aziz, S. and Thambyrajah, V. Eds). Malaysian Biochemical Society.
  67. Armugam, A. and Tan, N.H. (1988): Phospholipase A isoenzymes with anticoagulant activity and lethal toxicity from Malayan cobra venom (Naja naja sputatrix). In: Advances in Biochemistry and Biotechnology in Asia and Oceania (Sipat, A., Ampon, K., Perumal, P., Aziz, S. and Thambyrajah, V. Eds). Malaysian Biochemical Society.
  68. Tan, C.S., Armugam, A. and Tan, N.H. (1988): Acidimetric assay for phospholipase A using synthetic and natural substrate. In: Advances in Biochemistry and Biotechnology in Asia and Oceania (Sipat, A., Ampon, K., Perumal, P., Aziz, S. and Thambyrajah, V. Eds). Malaysian Biochemical Society.
  69. Kanthimathi, M.S. and Tan, N.H. (1988): Preliminary biochemical studies on the toxic and biologically active components of Malayan pit viper (Calloselasma rhodostoma) venom. Paper presented at the 7th FAOB Symposium, Nov 28th-30th, 1988. Kuala Lumpur, Malaysia.
  70. Tan, N.H. and Tan, C.S. (1989): The enzymatic activities and lethal toxins of Trimeresurus wagleri (Spekled pit viper) venom. Toxicon, 27, 349-357.
  71. Tan, N.H. and Saifuddin, Hj M.N. (1989): Enzymatic and toxic properties of Ophiophagus hannah (King cobra) venom and venom fractions. Toxicon, 27, 689-695.
  72. Tan, N.H. and Tan, C.S. (1989): Fractionation of Trimeresurus sumatranus sumatranus venom by DEAE-Sephacel ion exchange chromatography and investigation of the biological properties of the fractions. Toxicon, 27, 697-702.
  73. Tan, N.H., Arunmozhiarasi, A. and Tan, C.S. (1989): A comparative study of the enzymatic and toxic properties of venoms of the Asian lance-headed pit viper (Genus Trimeresurus). Comp. Biochem. Physiol. 93B, 757-762.
  74. Tan, N.H. and Arunmozhiarasi, A. (1989): Isolation and characterization of a lethal acidic phospholipase A from Malayan cobra (Naja naja sputatrix) venom. Biochemistry International, 18, 785-792.
  75. Tan, N.H., Poh, C.H. and Tan, C.S. (1989): The lethal and biochemical properties of Bungarus candidus (Malayan krait) venom and venom fractions. Toxicon 27, 1065-1070.
  76. Saifuddin, P. and Tan, N.H. (1989): Isolation and preliminary characterization of the L-amino acid oxidase from the king cobra (Ophiophagus hannah) venom. Proc. Mal. Biochem. Soc. 14, 97-101.
  77. Gnanajothy, P. and Tan, N.H. (1989): Comparative enzymology of krait (Genus Bungarus) venoms. Proc. Mal. Biochem. Soc., 14, 102-105.
  78. Tan, N.H. and Tan, C.S. (1989): Biochemical studies on temple pit viper (Trimeresurus wagleri) venom. Proc. Mal. Biochem. Soc., 14, 63-66.
  79. Arunmozhiarasi, A. and Tan, N.H. (1989): Studies on the anticoagulant activity of Malayan cobra venom. Proc. Mal. Biochem. Soc., 14, 106-109.
  80. Kanthimathi, M.S. and Tan, N.H. (1989): Hemorrhagic, phospholipase A, arginine ester hydrolase and clotting enzyme activities of the Malayan pit viper (Calloselasma rhodostoma) venom. Proc. Mal. Biochem. Soc., 14, 122-124.
  81. Tan, N.H., Tan, C.S. and Khor, H.T. (1989): Isolation and characterization of the major phospholipase A from the venom of Trimeresurus purpureomaculatus (shore pit viper).  Int. J. Biochem. 21, 1421-1425.
  82. Tan, N.H. and Arunmozhiarasi, A. (1989): The anticoagulant activity of Malayan cobra venom and venom phospholipase A. Biochemistry International 19, 803-810.
  83. Tan, N.H. and Saifuddin, M.N. (1989): Isolation and characterization of an unusual form of L-amino acid oxidase from king cobra (Ophiophagus hannah) venom.  Biochemistry International, 19, 937-944.
  84. Tan, N.H. and Gnanajothy, P. (1990): A comparative study of the biological activities of venoms from snakes of the genus Agkistrodon (Moccasins and Copper-heads). Comp. Biochem. Physiol. 95B, 577-582.
  85. Tan, N.H. and Saifuddin, M.N. (1990): Purification and characterization of two acidic phospholipase A enzymes from king cobra (Ophiophagus hannah) snake venom. International Journal of Biochemistry, 22, 481-486.
  86. Tan, N.H. and Gnanjothy, P. (1990): A comparative study of the biological properties of krait (Genus Bungarus) venoms. Comp. Biochem. Physiol. 95C, 105-109.
  87. Tan, N.H. and Gnanajothy, P. (1990): A comparative study of the biological activities of venoms from snakes of the genus Vipera. Comp. Biochem. Physiol. 96B, 683-688.
  88. Tan, N.H. and Saifuddin, M.N. (1990): Isolation and characterization of a hemorrhagin from the venom of Ophiophagus hannah (king cobra). Toxicon 28, 385-392.
  89. Tan, N.H. and Arunmozhiarasi, A. (1990): In vivo interaction between neurotoxin, cardiotoxin and phospholipase A enzymes isolated from Malayan cobra (Naja naja sputatrix) venom. Toxicon 28, 1193-1198.
  90. Tan, N.H., Saifuddin, M.N. and Nik Jaffar, M.I. (1990): Preparation of antibodies to king cobra (Ophiophagus hannah) venom hemorrhagin and investigation of their cross-reactivity. Toxicon 28, 1355-1359.
  91. Tan, N.H. and Gnanajothy, P. (1990): A comparative study of the biological properties of Australian elapid venoms. Comp. Biochem. Physiol. 97C, 99-106.
  92. Gnanajothy, P. and Tan, N.H. (1990): Differentiation between snakes of the genus Agkistrodon (mocassins and copperheads) by means of enzymatic activities of the venoms. Proc. Mal. Biochem. Soc., 15, 152-155.
  93. Yong, W.Y., Poh, C.H., Low, K.S., Tan, B.C. and Tan, N.H. (1990): Isolation of the tumor-localizing component of hematoporphyrin derivative using adsorption method. Proc. Mal. Biochem. Soc., 15, 156-158.
  94. Arunmozhiarasi, A. and Tan, N.H. (1990): Interaction between Malayan cobra venom cardiotoxin and phospholipase A. Proc. Mal. Biochem. Soc., 15, 24-26.
  95. Tan, N.H., Saifuddin, M.N. and Yong, W.Y. (1990): A study on the edema inducing activity of some snake venom phospholipase A.  Proc. Mal. Biochem. Soc., 15, 21-23.
  96. Cheah, C.H., Tan, N.H. and Khor, H.T. (1990): Oil and protein compositions of a groundnut (Arachis hypogaea L.) mutant Matjan Gamma 20. Proc. Mal. Biochem. Soc. 15, 188-191.
  97. Yeo, K.H., Jaafar, M.I.N. and Tan, N.H. (1990): Evaluation of the specificity of an indirect enzyme-linked immunosorbent assay (ELISA) for detection of Malayan pit viper venom and antibody. Proc. Mal. Biochem. Soc., 15, 148-151.
  98. Tan, N.H. and Saifuddin, M.N. (1990): A comparative study of the edema inducing activity of snake venoms. Comp. Biochem. Physiol. 97C, 293-296.
  99. Tan, N.H. and Saifuddin, M.N. (1991): Substrate specificity of king cobra (Ophiophagus Hannah) venom L-amino acid oxidase. Intn. J. Biochem. 23, 323-332.
  100. Tan, N.H. and Gnanajothy, P. (1991): A comparative study of the biological activities of rattlesnake (genus Crotalus and Sistrurus) venoms. Comp. Biochem. Physiol. 98C, 455-461.
  101. Tan, N.H., Arunmozhiarasi, A. and Gnanajothy, P. (1991): A comparative study of the biological activities of Dendroaspis (mamba) venoms. Comp. Biochem. Physiol. 99C, 463-66.
  102. Tan, N.H. and Gnanajothy, P. (1991): A comparative study of the biological properties of some sea snake venoms. Comp. Biochem. Physiol. 99B, 351-54.
  103. Tan, N.H., :Saifuddin, M.N. and Yong, W.Y. (1991): The edema inducing activity of phospholipase A enzymes. Biochemistry International 23, 175-181.
  104. Tan, N.H. and Gnanajothy, P. (1991): A comparative study of the biological properties of venoms of some old world vipers (Subfamily Viperinae). Int. J. Biochem., 24, 331-36.
  105. Tan, N.H. (1991): The Biochemistry of venoms of some venomous snakes of Malaysia—A review. Tropical Biomedicine, 8, 91-103.
  106. Tan, N.H. and Somasundaram, S. (1991): Purification and properties of L-amino acid oxidase from monocellate cobra (Naja naja kaouthia) venom. Int. J. Biochem. 24, 967-73.
  107. Tan, N.H. and Gnanajothy, P. (1991): A comparative study of the biological properties of venoms of snakes of the genus Bothrops (American lance-headed viper). Comp. Biochem. Physiol. 100B, 361-65.
  108. Tan, N.H. and Gnanajothy, P. (1992): The biological properties of venoms of some American coral snakes (Genus Micrurus). Comp. Biochem. Physiol. 101B, 471-74.
  109. Tan, N.H. and Gnanajothy, P. (1992): Biochemical characterization of snake venoms. In: Recent Advances in Toxinology Research (Gopalakrishnakone, P. and Tan, C.K. eds). Vol 1, pp210-258. National University of Singapore Press.
  110. Tan, N.H. and Tan, C.S. (1992): Phospholipase A isoenzymes of Trimeresurus purpureomaculatus (shore pit viper) venom. In: Recent Advances in Toxinology Research (Gopalakrishnakone, P. and Tan, C.K. eds). Vol 1, pp 625-35. National Univeristy of Singapore Press.
  111. Tan, N.H., Yeo, K.H. and Jaafar, M.I.N. (1992): Specificity of double-sandwich enzyme-linked immunosorbent assay (ELISA) of Malayan pit viper venom. Toxicon, 30, 556 (Abstract).
  112. Tan, N.H., Lim, K.K. and Jaafar, M.I.N. (1992): Enzyme-linked immunosorbent assay (ELISA) of the Malayan cobra (Naja naja sputatrix) and monocellate cobra (Naja kaouthia) venoms. Toxicon, 30, 556 (Abstract)
  113. Tan, N.H., Armugam, A., Mirtschin, P.J. and Masci, P. (1992): Comparative study of juvenile and adult taipan (Oxyuranus scutellatus) venoms. Toxicon 30, 555. (Abstract)
  114.  Tan, N.H., Thambyrajah, V. and Ariaratnam, P. (1992): The edema inducing activity of Malayan pit viper (Calloselasma rhodostoma) venom. In: Recent Advances in Toxinology Research (Gopalakrishnakone, P. and Tan, C.K. eds). Vol 1, pp 636-46. National Univeristy of Singapore Press.
  115.  Tan, N.H. and Yong, W.Y. (1992): The edema inducing activity of king cobra (Ophiophagus Hannah) venom proteases. In: Recent Advances in Toxinology Research (Gopalakrishnakone, P. and Tan, C.K. eds). Vol 1, pp 647-56. National Univeristy of Singapore Press.
  116.  Tan, N.H. and Gnanajothy, P. (1992): A comparative study on the electrophoretic patterns of snake venom. Comp. Biochem. Physiol. 102B, 103-110.
  117.  Tan, N.H. and Gnanajothy, P. (1992): Comparative study of the enzymatic, hemorrhagic, procoagulant and anticoagulant activities of some animal venoms. Comp. Biochem. Physiol. 103C, 299-302.
  118.  Tan, N.H., Armugam, A. and Mirtschin, P.J. (1992): The biological properties of venoms from juvenile and adult taipan (Oxyuranus scutellatus) snake. Comp. Biochem. Physiol. 103B, 585-588.
  119.  Tan, N.H., Yeo, K.H. and Nik Jaafar, M.I. (1992): The use of enzyme-linked immunosorbent assay for the quantitation of Calloselama rhodostoma (Malayan pit viper) venom and venom antibodies.  Toxicon 30, 1609-1620.
  120.  Tan, N.H., Armugam, A. and Chung, M.C.M. (1992): Preliminary studies on the amino acid sequencesof some Malayan cobra (Naja naja sputatrix) venom toxins. Proc. Mal. Biochem. Soc., 17, 171-174.
  121.  Tan, N.H., Wan Ismail, W.B. and Goh,S.H. (1992): Studies on oil palm fruit phosphatases and phospholipases. Proc. Mal. Biochem. Soc., 17, 259-261.
  122.  Tan, N.H. (1993): Calloselasma rhodostoma (IPCS monograph, W.H.O.)
  123.  Tan, N.H., Gonanajothy, P. and Mirtschin, P. (1993): A comparative study of the biological properties of venoms from juvenile and adult inland taipan (Oxyuranus microlepidotus) snake venoms. Toxicon, 31, 363-368.
  124.  Tan, N.H., Lim, K.K. and Nik Jaafar, M.I. (1993): An investigation on the antigenic cross-reactivity of Ophiophagus Hannah (king cobra) venom neurotoxin, phospholipase A, hemorrhagin and L-amino acid oxidase using enzyme-linked immunosorbent assay. Toxicon, 31, 865-72.
  125.  Gnanajothy, P., Chung, M.C.M. and Tan, N.H. (1993): Isolation and characterization of a hemorrahgin from the venom of Calloselasma rhodostoma (Malayan pit viper). Toxicon, 31, 997-1005.
  126. Tan, N.H., Gnanajothy P. and Mirtschin, P.J. (1993): A comparative study on the biological properties of venoms from juvenile and adult common tiger snake (Notechis scutatus) venoms. Comp. Biochem.Physiol. 106B, 651-654.
  127. Gnanajothy, P., Chung, M.C.M. and Tan, N.H. (1994): Purification and properties of the L-amino acid oxidase from Malayan pit viper (Calloselasma rhodostoma) venom. Arch. Biochem. Biophys. 313, 373-78.
  128. Tan, N.H., Choy, S.K., Chin, K.M. and Gnanajothy, P. (1994): Cross-reactivity of monovalent and polyvalent Trimeresurus antivenoms with venoms from various species of Trimeresurus (lance-headed pit viper) snake. Toxicon, 32, 849-853.
  129. Tan, N.H. and Gnanajothy, P. (1994): An investigation on the antigenic cross-reactivity of Calloselasma rhodostoma (Malayan pit viper) venom hemorrhagin, thrombin-like enzyme and L-amino acid oxidase using enzyme-linked immunosorbent assay. Toxicon, 32, 1265-1269.
  130. Tan, N.H., Iskandar, M.N.J. and Lim, K.K. (1994): The use of enzyme-linked immunosorbent assay for the quantitation of Enhydrina schistose (common sea snake) venom. Advances in Venom and Toxin Research (Tan, N.H., Oo, S.L., Thambyrajah, V. and Azila, N. Eds.). pp 274-278. Malaysian Society on Toxinology, Malaysia.
  131. Tan, N.H. and Lim, S.L. (1994):  Common antigens in Malaysian pit viper venoms and relative immunogeniticities of the venom proteins. Advances in Venom and Toxin Research (Tan, N.H., Oo, S.L., Thambyrajah, V. and Azila, N. Eds.). pp 259-263. Malaysian Society on Toxinology, Malaysia.
  132. Tan, N.H. and Choy, S.K. (1994): The edema inducing activity of Ophiophagus Hannah (king cobra) venom L-amino acid oxidase. Advances in Venom and Toxin Research (Tan, N.H., Oo, S.L., Thambyrajah, V. and Azila, N. Eds.). pp 274-278. Malaysian Society on Toxinology, Malaysia.
  133. Kee, P. and Tan, N.H. (1994): Evaluation of the trypsin treatment for experimental envenomation by poisonous snakes of Malaysia. Advances in Venom and Toxin Research (Tan, N.H., Oo, S.L., Thambyrajah, V. and Azila, N. Eds.). pp 264-267. Malaysian Society on Toxinology, Malaysia.
  134. Tan, N.H., Lim, K.K. and Iskandar, M.N.J. (1994): Kinetics of experimental envenomation by Ophiophagus Hannah (king cobra) venom. Toxicon 32, 541 (Abstract)
  135. Chung, M.C.M., Armugam, A. and Tan, N.H. (1994): Sequence analysis of the major hemorrhagin from the venom of Malayan pit viper (Calloselasma rhodostoma). Toxicon 32, 539 (Abstract)
  136. Chung, M.C.M., Armugam, A. and Tan, N.H. (1994): The amino acid sequence of two Malayan cobra venom neurotoxins. Toxicon 32, 539 (Abstract)
  137. Tan, N.H., Gnanajothy, P. and Mirtschin, P.J. (1994): Age-dependent variation in the venom of Australian common tiger snake (Notechis scutatus). Toxicon 32, 539 (Abstract)
  138. Tan, N.H., Choy, S.K. and Chin, K.M. (1994): Cross-reactivity of some Trimeresurus antivenoms with venoms of twelve Trimeresurus species. Toxicon 32, 542 (Abstract)
  139. Tan, N.H., Iskandar, M.N.J. and Lim, K.K. (1994): The antibody responses in rabbits immunizaed with king cobra (Ophiophagus Hannah) venom or venom components. Toxicon 32, 542 (Abstract)
  140. Vishna, D.V.N., Tan, N.H. and Choo, K.E. (1994): The use of enzyme-linked immunosorbent assay for immunodiagnosis of snake bite in northeast coast of Malaysia. Toxicon 32, 550. (Abstract)
  141. Tan, N.H., Oo, S.L., Thambyrajah, V. and Azila, N. (1993).  Advances in Venom and Toxin Research. Malaysian Society on Toxinology, Malaysia.
  142. Tan, N.H., Baharuddin, W.I. and Goh, S.H. (1994); Phosphatases and phospholipase D from oil palm fruits. Proceedings of Oils and Fats International Congress, September 5th-8th, 1994, Kuala Lumpur, Malaysia. p31.
  143. Chung, M.C.M., Tan, N.H. and Arunmozhiarasi, A. (1994): The amino acid sequence of two postsynaptic neurotoxins isolated from Malayan cobra (Naja naja sputatrix) venom. Toxicon 32, 1471-1474.
  144. Ong, S.H., Poh, Y.K., Tan,N.H. and Chung, M.C.M. (1995): Analysis of snake venom proteins by 2-dimensional gel electrophoresis. Paper presented at the 3rd International Union of Biochemistry and Molecular Biology Conference, “Molecular Recognition” 23rd-27th April, 1995, Singapore.
  145. Chung, M.C.M., Tan, N.H. and Gnanajothy, P. (1995): Structural analysis of the major hemorrhagin from Calloselasma rhodostoma (Malayan pit viper) venom. Paper presented at the 3rd International Union of Biochemistry and Molecular Biology Conference, “Molecular Recognition” 23rd-27th April, 1995, Singapore.
  146. Armugam, A., Lachumanan, R., Earnest, L., Tan, N.H., Gopalakrishnakone, P., Tan, C.H. and Jeyaseelan, K. (1995): Cloning and characterization of cDNA encoding two different neurotoxins in the venom of Naja naja sputatrix. at the 3rd International Union of Biochemistry and Molecular Biology Conference, “Molecular Recognition” 23rd-27th April, 1995, Singapore.
  147. Armugam, A., Earnest, L., Tan, N.H., Gopalakrishnakone, P., Tan, C.H. and Jeyaseelan, K. (1995): Cloning of cDNAs encoding the phospholipases in Naja naja sputatrix and expression of the structural genes in Escherichia coli. at the 3rd International Union of Biochemistry and Molecular Biology Conference, “Molecular Recognition” 23rd-27th April, 1995, Singapore.
  148. Jeyaseelan, K., Armugam, A., Earnest, L., Yeo, M.S.L., Lachumanan, R., Tan, N.H., Gopalakrishnakone, P. and Tan, C.H. (1995): Molecular cloning of genes encoding toxins in the venom of Naja naja sputatrix. at the 3rd International Union of Biochemistry and Molecular Biology Conference, “Molecular Recognition” 23rd-27th April, 1995, Singapore.
  149. Chung, M.C.M., Gnanajothy, P., Kataoka, M., Shimizu, S. and Tan, N.H. (1996): Structural studies of a major hemorrhagin (rhodostoxin) from the venom of Calloselasma rhodostoma (Malayan pit viper). Arch. Biochem. Biophys. 325, 199-208.
  150. Daltry, J.C., Gnanajothy, P., Chai, K.S., Tan, N.H., Thorpe, R.S. and Wolfgang, W. (1996): Electrophoretic profiles and biological activities: Intraspecific variation in the venom of the Malayan pit viper (Calloselasma rhodostoma). Toxicon 34, 67-69.
  151. Tan, N.H. and Gnanajothy, P. (1996): The toxinology of Calloselasma rhodostoma (Malayan pit viper) venom. Toxin Reviews 15, 1-17.
  152. Armugam, A., Earnest, L., Chung, M.C.M., Gopalakrishnakone, P., Tan, C.H., Tan, N.H. and Jeyaseelan, K. (1997): Cloning and characterization of cDNAs encoding three isoforms of phospholipase A in Malayan spitting cobra (Naja naja sputatrix) venom. Toxicon 35, 27-37.
  153. Tan, N.H., Gnanajothy, P. and Chung, M.C.M. (1997): Proteolytic specificity of rhodostoxin, the major hemorrhagin of Calloselasma rhodostoma (Malayan pit viper) venom. Toxicon 35, 979-984.
  154. Afifiyan, F., Armugam, A., Tan, N.H., Tan, C.H. and Jeyaseelan, K. (1997): Cloning of genes encoding isoforms of a-neurotoxins in Naja naja sputatrix venom. Toxicon, 36, 1294.
  155. Afifiyan, F., Armugam, A., Tan, N.H., Tan, C.H. and Jeyaseelan, K. (1997): Cloning and sequence analysis of genes encoding phospholipase A in the venom of Naja naja sputatrix.  Toxicon 36, 1296.
  156. Gnanajothy, P. and Tan, N.H. (1998): Serum kinetics of Calloselasma rhodostoma (Malayan pit viper) venom and venom components in a rabbit injected with a non-lethal dose of C.rhodostoma venom. Paper presented at the Symposium on Animal, Plant and Microbial Toxins (Natural Toxins of Malaysia), 28th Feb, 1998, Kuala Lumpur, Malaysia.
  157. Tan, N.H. (1998): Protection against Malaysian snake envenomations: comparative potency of some commercial and laboratory-prepared antivenoms. Paper presented at the Symposium on Animal, Plant and Microbial Toxins (Natural Toxins of Malaysia), 28th Feb, 1998, Kuala Lumpur, Malaysia.
  158. Lu, G.J. and Tan, N.H. (1998): Thrombin-like enzyme from Trimeresurus purpureomaculatus (Mangrove pit viper) venom. Paper presented at the Symposium on Animal, , Plant and Microbial Toxins (Natural Toxins of Malaysia), 28th Feb, 1998, Kuala Lumpur, Malaysia.
  159. Jeyaseelan, K., Armugam, A., Lachumanan, R., Tan, C.H. and Tan, N.H. (1998): Six isoforms of cardiotoxin in Malayan spitting cobra (Naja naja sputatrix) venom: Cloning and characterization of cDNAs. Biochim. Biophys. Acta 1380, 209-222.
  160. Tan, N.H. (1998): L-Amino Acid Oxidases and Lactate Dehydrogenases. In: Enzymes From Snake Venom, (Bailey, G.S. Ed.), Chapter 19, pp.579-598. Alaken Inc, Fort Collins, U.S.A.
  161. Tan, N.H. (1998): Kistomin (Calloselasma rhodostoma). In: Handbook of Proteolytic Enzymes (Barratt, A., Rawlings, N.D. and Woessner, J.F. Eds.) pp1287-1290. Academic Press, London.
  162. Afifiyan, F., Armugam, A., Gopalakrishnakone, P., Tan, N.H., Tan, C.H. and Jeyaseelan, K. (1998): Four new postsynatpci neurotoxins from Naja naja sputatrix venom: cDNA cloning, protein expression and phylogenetic analysis. Toxicon 36, 1871-1876.
  163. Lu, G.J. and Tan, N.H. (1998): Thrombin-like enzyme from Trimeresurus purpureomaculatus (Mangrove pit viper) venom. Paper presented at the 8th Federation of Asian and Oceanian Biochemists and Molecular Biologists Congress, 22nd-26th November, 1998, Kuala Lumpur, Malaysia.
  164. Chuman, Y., Nobuhisa, I., Ogawa, T., Deshimaru, M., Chijiwa, T., Tan, N.H., Fakumaki, Y., Shimohigashi, Y., Ducancel, F., Boulain, J.C., Menez, A. and Ohno, M. (1999): Regional and accelerated molecular evolution in group I snake venom gland phospholipase A isoenzymes. Toxicon 38, 449-462.
  165. Tan, N.H., Alhady,S.F., Azila, N.A., Nah,S.H., Sim, S.M., Ismail,R., Al-Sadat, N.S.A.M., Atiya, A.S. and Arumainathan, U. (2000): Introducing problem based learning element in the New Integrated Curriculum of the MBBS course at University of Malaya: an appraisal of the issues in the implementation. In: Implementing Problem Based Learning. The Problem-Based Learning Project, University of Hongkong, Hongkong, 2000, pp347-354.
  166. Azila, N.M.A., Alhady, S.F., Tan, N.H., Atiya, A.S., Nah, S.H., Sim, S.M., Ismail, R., Nabilla, A. and Arumainathan, U. (2000): Adaptative changes towards problem based learning in the New Integrated Curriculum (NIC) of the Medical Course at the University of Malaya. In: Implementing Problem Based Learning. The Problem Based Learning Project, University of Hongkong, Hongkong 2000, pp323-332.
  167. Alhady, S.F., Anuar, Z., Azila, N.M.A., Sim, S.M., Tan, N.H., Cheah, S.H., Khairul Anuar, A., Tan, C.P.L., Iekhsan, O., Liam, C.K., Mohd Amin J., Rosnani, A.A. and Parasakthi, N. (2000): Towards quality management enhancement of the New Integrated Curriculum of the Faculty of Medicine, University of Malay. In: Implementing Problem Based Learning. The Problem Based Learning Project, University of Hongkong, Hongkong, 2000, pp317-322.
  168. Jeyaseelan, K., Armugam, A., Donghui, Ma and Tan, N.H. (2000): Structure and phylogenyof venom group I phospholipase A.  Molecular Biology and Evolution, 17, 1010-1021.
  169. Fung, S.Y. and Tan, N.H. (2000): Isolation of maculatoxin, the major hemorrhagin from Trimeresurus purpureomaculatus (mangrove pit viper) venom. Paper presented at the 25th Annual Conference of the Malaysian Biochemical Society and Molecular Biology, Kuala Lumpur, Malaysia.
  170. Tan, N.H., Atiya, A.S., Azila, N.M.A., Sim, S.M., Cheah, S.H. and Husain, R. (2000): Early response by students and facilitators towards problem-based learning programme in the medical curriulum of the University of Malaya. Paper presented at the First Asean Conference on problem Based Learning in Health Sciences, Nov 20th-22nd, 2000, Singapore.
  171. Tan, N.H. (2001): Changes to Paradigm Shift –The New Integration Curriculum. Paper presented at “Innovations in Medical Education”, International Medical University, Kuala Lumpur, 20th-21st, February, 2001.
  172. Tan, N.H. (2001): Biomedical studies and genetic engineering of snake venom toxins. Proceedings of RMK 7 IRPA Research Seminar, 24th-25th July 2001, University of Malaya. Pp.276-279.
  173. George, J., Thong, M.K., Sherina, N., Khoo, M.T., Tan, N.H. and Azila, N.M.A. (2001): Preliminary experience with problem based learning in early clinical year at the University of Malaya Medical Faculty. Paper presented at the 2nd Asia Pacific Conference on Problem Based Learning in Health Sciences, October 2001, Kuala Lumpur.
  174. Junedah, S., Azila N.M.A., Tan, N.H., Atiya, A.S, Cheah, S.H., Husain, R. and Sim, S.M. (2001): Prblem based learning in Faculty of Medicine, University of Malaya: Does early experience improve perception toward PBL? Paper presented at the 2nd Asia Pacific Conference on Problem Based Learning in Health Sciences, October 2001, Kuala Lumpur.
  175. Azila, N.M.A., Tan, C.P.L., Sim, S.M., Tan, N.H., Atiya, A.S. and Junedah, S. (2002):  Problem based learning: Monitoring and searching for an appropriate tune. Journal of Medical Education, 6, 68-73.
  176. Azila, N.M.A., Tan, N.H. and Kwan, C.Y. (2992): Quality Assurance in Problem Based Learning. Journal of Medical Education, 6, 1-2.
  177. Chong, Y.J. and Tan, N.H. (2002): Phospholipase A from Bungarus candidus (Malayan krait) venom. Paper presented at the 27th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 7th October, 2002, Kuala Lumpur.
  178. Tan, N.H. (2002): Biomedical studies on Snake Venoms. Exhibition at Expo Sains & Teknologi Malaysia. Nov 2nd-4th, 2002, PWTC, Kuala Lumpur, Malaysia.
  179. Tan, N.H. and Fung, S.Y. (2002): A hemorrhagic toxin from the venom of Trimeresurus purpureomaculatus snake (Mangrove pit viper). European Journal of Biochemistry 269, 99.
  180. Sim, S.M., Tan, N.H., Rosnah, I., Liam, C.K., Atiya, A.S. and Azila, N.M.A. (2002): Appraisal of critical thinking development in a ‘hybrid’ PBL program. Paper presented at the 3rd Asia Pacific Conference on Problem-Based Learning in Health Sciences, October, 2002, Taiwan, ROC.
  181. Tan, N.H., Azila, N.M.A., Sim, S.M., Rosnah, I., Thong, M.K., Liam, C.K. and Tan, C.P.L. (2002): The problem of students’ mindsetand the implementation of PBL program in a hybrid PBL curriculum. Paper presented at the 4th Asia-Pacific Conference on Problem-based Learning. December 11th-13th, 2002, Hatyai, Thailand.
  182. Azila, N.M.A., Sim,S.M., Tan, N.H., Atiya, A.S., Fung, S.Y. and Tan, C.P.L. (2002): Student performance assessment in a hybrid PBL program. Paper presented at the 4th Asia-Pacific Conference on Problem-based Learning. December 11th-13th, 2002, Hatyai, Thailand.
  183. Sim,  S.M., Tan, N.H., Cheah, S.H., Chan, W.K. and Rashidah, B. (2002): Evaluating critical thinking and learning approach preferences of pre-clinical medical students at the University of Malaya, Malaysia. Paper presented at the 4th Asia-Pacific Conference on Problem-based Learning. December 11th-13th, 2002, Hatyai, Thailand.
  184. Tan,  N.H., Fung, S.Y., Ponnudurai, G. and Chung, M.C.M. (2003): Epitope mapping of rhodostoxin, the major hemorrhagin from Calloselasma rhodostoma venom.  Exhibition at Expo Sains & Teknologi Malaysia. Augudst 7th-9th, 2003, PWTC, Kuala Lumpur, Malaysia
  185. Tan, N.H., Fung, S.Y. and Lu, G.J. (2003): Immunological properties of thromin-like enzymes from Trimeresurus purpureomaculatus and Trimeresurus albolabris. Paper presented at the 28th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 12th August, 2003, Putra Jaya, Malaysia.
  186. Chong, Y.J. , Tan, N.H. and Debra, Sim, S.M. (2003): Preliminary investigation of the toxicological properties of the Malayan krait (Bungarus candidus) venom. Paper presented at the 28th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 12th August, 2003, Putra Jaya, Malaysia
  187. Azila, N.M.A., Tan, N.H., Sim, S.M., Rosnah, I., Liam, C.K. and Atiya, A.S. (2003): Critical thinking development in a ‘hybrid’ Problem-Based Learning programme. J. Med. Edu. 7, 306-312 .
  188. Chong, Y.J., Tan, N.H., Geh, S.L. and Sim, S.M. (2004) Pharmacological characterization of the Bungarus candidus (Malayan krait) venom and one of its phospholipase A2. Paper presented at the 19th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, May 17th-18th, 2004, University of Malaya.
  189. Marinello, E., Guerranti, R., Pagani, R., Aguiyi, J.C., Tan, N.H. and Fung, S.Y. (2004) Immunological cross-reactions between snake venoms and anti-Mucuna pruriens IgG. Paper presented at the 29th FEBS Congress, 26th June-1st, July, 2004. Warsaw.
  190. Tan, N.H (2004): The Biochemistry of Malayan Pit Viper Venom. Third Asia-Pacific Congress on Thrombosis and Hemostasis. Oct 14th-16th, 2004, Bangkok, Thailand.
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